On Sunday, Marco Rubio decisively won in Puerto Rico while Sanders easily won in Maine.
Cruz's victory in the Kansas caucuses became the fifth for him as he previously dominated in Iowa, Oklahoma, Alaska and his native state of Texas. While he said he "can't imagine" being elected by delegates at the party's Cleveland convention in July, he added, "I don't think anyone in our party should say, 'Oh no, even if the people in the party wanted me to be president, I would say no to it'".
Saturday's Republican races also included Maine, Kentucky and Louisiana, while Democrats voted in Nebraska, Kansas and Louisiana.
Trump picked up additional delegates in Saturday voting, too, with victories in Kentucky and Louisiana.
On the Democratic side, Clinton hoped that strong support among African Americans in Louisiana would propel her to victory.
Donald Trump is leading Marco Rubio in the Florida senator's home state by 8 percentage points, a Monmouth University poll out Monday shows.
If Trump wins the nomination, three-quarters of Republican voters in the Sunshine State said they would support him in a general election match-up against Hillary Clinton.
"If Ted's the alternative to Trump, he's at least a Republican and conservative", South Carolina Sen.
Republican National Committee Chairman Reince Priebus said he "highly" doubted that a front-runner would head to the convention in Cleveland without having already secured the 1,237 delegates needed to win the first ballot.
"Here's the bottom line". A loss in Florida, his home state, which votes on Tuesday March the 15th, will effectively end his campaign. "It's a winner-take-all state", he said. "So tonight, we will have more delegates than we did last night".
Former US State Secretary Hillary Clinton won only one but the largest state out of three, Louisiana, which allowed her to beat Sen.
"We have allowed our politics to be hijacked by extreme ideologues". She said she liked the businessman because "he's not bought and paid for".
After Saturday's voting, Clinton has 1,117 delegates versus Sanders' 477.
On the other hand, the victory by Cruz in Kansas appears to fit squarely into historical precedent.