"The ministry said the man had immediately started shooting when police and members of a special task force raided his apartment".
There are conflicting reports as to the circumstances around the situation. "Four police officers were injured, some seriously".
German police say four officers have been shot and wounded during a raid in which they had planned to confiscate the weapons of an anti-government extremist.
German media reported the man was a "Reichsbürger" (roughly translating to "citizen of the Reich") - a right-wing extremist who rejects the power of the current German state. The 49-year-old German man had legally possessed more than 30 weapons for hunting, but local authorities had revoked his license because he appeared increasingly unreliable, Hermann said.
Germany remains on a state of high alert following a series of terror attacks by Isis supporters, including a suicide bombing in Ansbach and axe attack on a train. Herrmann said those measured would have to be stepped up further - though he said some members of the Reich movement aren't necessarily extremists or potentially violent.
Centres for asylum seekers have been the target of arson attacks and racist graffiti, while police uncovered a neo-Nazi plot to attack refugee accomodation with explosives past year.