Biden, campaigning for Democratic presidential nominee Hillary Clinton in Wilkes-Barre, Pennsylvania, addressed recent allegations from multiple women who say Trump acted inappropriately toward them.
Biden said, "Ladies and gentlemen, this guy is far beyond a bad character with women".
"No, I wish we were in high school", Biden added. "He said, 'because I'm famous, because I'm a star, because I'm a billionaire, I can do things other people can't!' What a disgusting assertion for anyone to make!"
Trump campaign manager Kellyanne Conway and pollster Frank Luntz both accused the media of a double standard in the reporting on Biden's statement.
The Biden's oldest son, Beau, died from brain cancer in 2015. "I want the public knowing the Hillary I know", he said.
The announcement of Biden's "Moonshot" effort in January came a day after the Windber hospital and research institute's financial backer, Dr. Patrick Soon-Shiong, announced his own Cancer MoonShot 2020 with a similar goal.
He said he was forced to travel to Europe to reassure North Atlantic Treaty Organisation allies that America would not abandon them.
The vice president also slammed Trump's refusal to accept the results of the election if he loses, calling it a "threat to the democratic process". "Everywhere I go I get asked by world leaders, 'This can't be true can it?'"
"Donald Trump is already doing damage to us", Biden said.