The assailants were shot dead by the police. Three perpetrators of the attack were shot dead by police in the mosque's yard. A third Palestinian sustained fatal injuries during a riot at the Abu-Dis village near Jerusalem, and later died of his wounds in a hospital in Ramallah, according to Maan. Al Jazeera quoted local media as saying that the man, thought to be aged 17, was killed by an Israeli settler in the Ras al-Amud neighbourhood. No injury toll was given for the West Bank.
Jerusalem District Police Commander Major-General Yoram Halevy had ordered the site to be closed for Jews after a group of Jewish visitors breached the rules and entered the site with prayer books and attempted to pray.
This included the installation of metal detectors, which Palestinian and Islamic leaders say undermines the fragile set of arrangements agreed after Israel took control of the Old City during the Six-day War in 1967.
"We express. our grief for the loss of human life and strongly condemn any act of violence", the Christian leaders said.
Palestinian president Mahmud Abbas spoke with USA counterpart Donald Trump´s senior adviser and son-in-law Jared Kushner.
Abbas stressed that the situation was "extremely risky and might spiral out of control", the media outlet added. The Waqf also rejected the metal detectors. He spoke by telephone with both Mr Abbas and Israeli president Reuven Rivlin on Thursday.
Friday prayers are frequently a flashpoint for protests and unrest in Jerusalem and the West Bank, with police severely restricting Muslim access to the area surrounding the al-Aqsa mosque and setting up checkpoints.
The main weekly prayers on Fridays draw the largest number of worshippers - typically thousands - and speculation had been mounting that Mr Netanyahu might order the metal detectors removed.
"I want to tell Israel and the world that if Israel wants peace they have to immediately remove the metal doors and other security obstacles they put in the last week", he told regional news site Middle East Eye on Thursday.
But by early afternoon, with police mobilising extra units and placing barriers to carry out checks at entrances to the Old City, there had been little serious violence.
The attack is the latest manifestation of growing tensions over the Temple Mount since the Israeli Arab terrorist attack.
The compound was reopened Sunday with metal detectors installed, a step Palestinians protest as a change to the longstanding status quo.