Destiny 2 is undoubtedly going to be a popular game, but it seems that anyone who may want to take advantage of that popularity and stream footage of it to Twitch or YouTube is in for some frustration.
Hardware capture through methods such as Elgato, AVerMedia, or a dedicated streaming PC is supported.
Loads of PC gamers are waiting patiently for the Destiny 2 Beta that is scheduled for the end of this month. Bungie also notes that both AMD ReLive and NVIDIA Shadowplay are supported. It includes the checking of the functionality of "Destiny 2" on a new gaming platform to allow PC players to have the first dibs on the game, as well as to open up a venue to incorporate added surprises for the final edition of the best-selling shooter video game's sequel. Namely streaming he game in Windowed mode. Windowed Mode/Borderless Fullscreen does not have these restrictions, and you can use OBS and XSplit here instead. Notification features may still be provided through the third-party application.
Overlays Some features from third-party applications which rely on the use of screen overlays are generally not compatible with Destiny 2.
Bungie discussed that main aim of the game's PC beta in its latest community update on its website.
These incompatibilities also extend to voice and hardware monitoring applications as well.
PLEASE NOTE: Third-party applications which repeatedly attempt to insert code into the Destiny 2 PC client may potentially impact game performance.
Destiny 2 PC beta will start on August 28 only for players who pre-ordered the game.