The Sixers ruled him out of Game 2 of their playoff series against the Miami Heat, Monday at Wells Fargo Center.
Embiid hasn't played since suffering an orbital fracture and concussion against the New York Knicks on March 28.
Embiid had told ESPN's Ramona Shelburne prior to Saturday night's playoff opener that he was optimistic about playing in Game 2 or 3.
Veteran Amir Johnson will likely start in place of the injured Embiid in Game 1 of the Sixers' first-round playoff series.
Reserve swingman Timothe Luwawu-Cabarrot will also miss Monday's game with right knee patellar tendinitis.
No exact timetable was given for his return, but Embiid will wear a protective mask when he returns to the court.
Coach Brett Brown shrugged when asked if Embiid's return, or lack thereof is linked to the success the Sixers have had without them.
Delon Wright and CJ Miles each had big games off the bench, combining for 30 points for the top-seeded Raptors, who snapped a streak of 10 straight Game 1 losses. The club is 9-0 without its All-Star center, who averaged 22.9 points, 11.0 rebounds and 1.8 blocks in 63 games in the regular season. So we got a pretty good chance for Game 2 or Game 3.
Guard J.J. Redick practiced Sunday and pronounced himself fit after his scary moment in Game 1.
"I feel fine", Redick said. The third seed in the East torched their conference rival by 27 points, 130-103, as Ben Simmons almost marked a triple-double in his first playoff game.