Seven people have been critically injured, including a 16-year-old boy who was shot in the face.
Forty Palestinians, including five children and two journalists, have been killed during the Great March of Return protests that were launched on 30 March.
Despite Israel's repeated use of lethal force, Gaza residents once again flocked toward the Israeli border on Friday, to demand the right of return to their homelands and to reject US recognition of Jerusalem as Israel's capital.
Citing data from the Palestinian Ministry of Health in Gaza, the aid charity Save the Children reported on Friday that at least 250 Gazan children had been shot with live ammunition during the protests, among around 700 children wounded overall.
Evans is celebrating the bold stand of President Trump to recognize Jerusalem as the capital of Israel and now is moving the US Embassy from Tel Aviv to Jerusalem.
He said demonstrators are burning tyres, throwing rocks against the border fences and at soldiers, and using incendiary kites to set fire to the nearby Israeli farmland.
Hamas leader in the Gaza Strip, Yahya Sinwar, center, chant slogans as he surrounded by protesters during his visit to the Gaza Strip's border with Israel, Friday, April 20, 2018. Some of the protesters, mainly youths, brandished wire cutters, a popular tool in weekly attempts to cut through the border fence.
In a statement on Friday, the Israel Defense Forces said about 5,000 Palestinians were taking part in "riots" along the border.
Mass rallies are planned for Monday, the eve of Nakba Day - the annual commemoration of the ethnic cleansing of the Palestinian homeland and before, during and after the declaration of the state of Israel on 14 May 1948. Israel will not allow the destruction of infrastructure at the border, said the IDF spokesperson.
Witnesses said Israeli forces on the other side of the fence had added reinforcements, including cement slabs, as protective cover. Israel and Egypt maintain an economic blockade of the strip, which has the highest unemployment rate in the world and has become far poorer than the other main Palestinian territory, the Israeli-occupied West Bank. Hundreds of thousands of Palestinians were driven out or fled homes in what is now Israel.