It's the fourth time in Mariners history that a pitcher has hurled at least 16 strikeouts. The A's pressured Paxton throughout the game with leadoff hits, but he was able to strike out batters and get out of multiple jams to keep his shutout alive.
The Mariners opened the scoring in the third inning against left-hander Brett Anderson, who was making his first start for the A's since 2013 and his first this season. Lowrie tied the score in the eighth with a two-run homer off Juan Nicasio.
Ryon Healy, acquired from Oakland in an offseason trade, led off with a home run to left-center field on a 2-1 pitch.
Paxton also did his home country proud by passing Erik Bedard (July 7, 2007) for the most strikeouts in a single game by a Canadian pitcher in modern Major League Baseball history, according to TSN's StatsCentre.
The right-hander walked Khris Davis to lead off the frame and Matt Olson doubled to right, ending Hernandez's outing.
Juan Nicasio pitched a ideal eighth for the Mariners, striking out two to set it up for Diaz.
The Mariners loaded the bases with one out in the bottom of the inning but failed to score as Blake Treinen (2-1) struck out Nelson Cruz and Mitch Haniger. Dee Gordon reached on an infield hit, but the tying run was forced to stay at third base, as the score remained 3-2. The Mariners recalled OF Guillermo Heredia and RHP Casey Lawrence from Triple-A Tacoma.
The pitcher threw 105 pitches in his seven-inning start, including 80 strikes, thirty of which were swinging strikes, the most in baseball this season.
Paxton saw his earned run average drop from 5.12 to 4.19 with Wednesday's quality start.