The actor had struggled with health issues in recent years and underwent major heart surgery in February 2010.
In 1977, Reynolds made "Smokey and the Bandit", which took in over $100 million at the box office and spawned two sequels. Still, he'll be remembered by more than one generation for the likes of The Cannonball Run, The Player and his Oscar-nominated role in Boogie Nights.
"If I had to put only one of my movies in a time capsule, it would be Deliverance", Reynolds wrote in his 2015 memoir But Enough About Me.
"I didn't open myself to new writers or risky parts because I wasn't interested in challenging myself as an actor".
"As a result, I missed a lot of opportunities to show I could play serious roles".
The actor first stepped into Hollywood in 1961's George Hamilton-led Angel Baby. But Reynolds never had any regrets for how his life turned out.
He launched his acting career with TV shows like "Gunsmoke" and "Dan August", but his breakout film role was in "Deliverance" in 1972.
He would later call Field "the one that got away".
Smith has always been an outspoken fan of Reynolds, with either the actor himself or the Smokey and the Bandit films being referenced in numerous films and other projects Smith has developed. "He was a trailblazer", Schwarzenegger said in a tweet. "My thoughts are with his family".
An iconic Hollywood sex symbol in front of the camera, Reynolds also tried his directorial hand behind it, and later earned a reputation for philanthropy after founding the Burt Reynolds Institute for Film & Theatre in his home state of Florida.
FSU Football shared a photo of Reynolds in his football uniform with the caption "RIP Burt". "Always warm and amusing", tweeted comedian Ricky Gervais.