Meanwhile, Kane's strike in the Midlands means that he's scored in 27 of his last 27 league away games, a tally he will be bidding to enhance away to Crystal Palace next weekend, although first off he has a crunch Champions League clash at home to PSV to look forward to.
The win, Spurs' first of the group stage, leaves them in third place, three points behind Inter Milan, who visit Wembley in three weeks.
"I think for me the most important thing..."
PSV 'keeper Zoet does his best to make a save.
It took time for them to regroup and, when they did in the 19th minute, substitute Son Heung-min found Kane and his low effort was turned away by Rui Patricio.
The visiting defense was finally breached when Kane met a lay-off from substitute Fernando Llorente with a left-footed shot into the corner.
Kane was to the fore once again in the dying embers of the contest, his headed attempted clipping Sainsbury on its way into the net to leave PSV on the brink of elimination. Luuk de Jong with the header!
The current European champions have struggled in all competitions this season - sitting sixth on the Spanish League table with 17 points from 11 matches.
Spurs and PSV are both in dire need to a win to keep their faint qualification hopes alive.
If they don't win tonight, the Champions League is surely over.
"We achieved one, two and in the last 10 minutes, anything can happen", he added. This is why Hugo Lloris will be starting between the sticks instead of Paulo Gazzaniga.
Dembele joined knee injury victim Victor Wanyama on the sidelines along with Eric Dier, who is nursing a thigh problem, to leave young England prospect Harry Winks as the only specialist central midfielder at Pochettino's disposal.
Dele Alli will likely be able to play against PSV.
Wrong substitutions and failing to spot danger There were five minutes of normal time left in Milan and Tottenham were leading 1-0 in their opening group game.
The match is on Tuesday 6 November with kick-off at 8pm at Wembley.
Two weeks ago, PSV were terrible against Tottenham and didn't deserve to get a point.
He is weighing up a move for £20m-rated Espanyol defender Mario Hermoso, with club scouts making several trips to watch the 23-year-old this season.
Any side outside of the top three or four in the Premier League are terrified of City and even though they are a fine team, they have an aura that is intimidating opponents into submission before a ball is kicked.