First baby born using uterus transplant from dead donor, doctors say

This successful case may offer women with uterine infertility a greater chance to carry and give birth to a baby without the risk of major surgery for live donors, the Lancet case study authors at the University of Sao Paulo Faculty of Medicine Clinics Hospital wrote.

The recipient in the groundbreaking case was a 32-year-old woman born without a womb due to a rare genetic disorder.

He said live uterus donors are rare and typically eligible family members or close friends of women seeking the transplant.

The Brazilian researchers are planning two more uterus transplants as part of the study.

The oldest child born via uterine transplant - a boy - had just had his fourth birthday.

The procedure involved connecting the donor uterus to the veins, arteries, ligaments and vaginal canals of the 32-year-old.

"She couldn't keep the uterus in another pregnancy", said Dr. Wellington Andraus, who worked on her transplant team.

Unlike most transplantation surgeries "this is not a matter of life and death but more to satisfy a woman's desire to carry a child", Professor Salamonsen said.

Experts hope uterus transplants will one day be more widely available for women without uteruses or with damaged organs - or potentially even transgender women - seeking to become pregnant.

Knowing this could make all the difference not just when it comes to deceased donations, but live ones as well.

Since live uterus donors are a limitation, the report shows that uterus transplants from deceased donors are feasible and may open access for all women with uterine problems, without the need for live donors, as is the practice now.

Infertility affects 10 to 15 percent of couples. Though there have been 10 uterus transplants from deceased donors in the United States, the Czech Republic and in Turkey, this is the first to result in a child.

The woman's pregnancy was normal, and doctors performed a Caesarean section on December 15, 2017, after about 36 weeks (a full term is about 40 weeks).

Doctors said the breakthrough operation was the first successful case of its kind.

"The use of deceased donors could greatly broaden access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility."the lancet quoted the lead researcher Dr Dani Ejzenberg, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo".

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it. It is estimated that one woman out of 500 would be the victim of an abnormality of the uterus into the world.

While researchers in countries including Sweden and the U.S. have previously succeeded in transplanting wombs from living donors into women who have gone on to give birth, experts said the latest development was a significant advance.

The first living donor womb transplant was performed in Sweden in 2013.

Four months before the transplant, she had in-vitro fertilisation resulting in eight fertilised eggs, which were preserved through freezing. In the first, the uterus had to be removed from the recipient after an infection occurred; Flyckt said she couldn't say where things stood with the second case other than that the recipient was doing well.

Mother and baby left the hospital three days later. The donated uterus was then removed from the patient after the birth. At the age of 7 months and 20 days, the baby continued to breastfeed and weighed 15 pounds, 14 ounces.

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