The day-long protest left commuters leaving London facing a chaotic journey home with thousands of demonstrators blocking key transport hubs during a co-ordinated day of action at five landmarks.
But activists camped overnight to ensure blockades continued at Waterloo Bridge, Millbank and Oxford Circus.
The "Extinction Rebellion" protestors have promised to continue their action throughout the week.
CNN noted, "Extinction Rebellion, which launched late past year with climate protests that shut down five London bridges, made headlines earlier this month when members of the group disrupted a Brexit debate in Parliament with a nude demonstration".
Rowan McLaughlin, 47, a teacher, said this week's protests were more important that the huge pro and anti-Brexit protests in London recently. "We wish to make peace with ourselves by making peace with our neighbour Earth and with our God".
The group has three demands: for the government to "tell the truth about climate change", reduce carbon emissions to zero by 2025, and create a citizens' assembly to oversee progress.
The Metropolitan Police have said they have "appropriate" plans in place and that officers will be used "to support the public order operation during the coming weeks".
There were loud cheers, the ringing of bells, and the blowing of whistles as people were quickly arrested and taken to police vans. This crisis is only going to get worse Prime minister, you can not ignore this crisis any longer.
"In London, people are willing to be arrested and to stay". Police report that 122 demonstrators have been arrested.
The majority of these arrests were made for breaching Section 14 of the Public Order Act 1986 and obstructing a highway.
At Waterloo Bridge, protesters blocked the crossing over the Thames and turned it into an impromptu garden bridge, with people bringing trees, flowers and setting up a miniature skate park and stage.
Blythe Pepino, 34, from Hereford, said: "The goal is to maintain the disruption on the bridge to bring the Government to the table and talk about the climate crisis".