The craft was carrying a humanoid robot that was scheduled to conduct a mission on the station with the cosmonauts who are there.
The problem, Russian flight controllers said, appears to be a problem with the Kurs automated docking system on the ISS, and not a problem with the Soyuz spacecraft itself.
Russian space agency Roscosmos reported that there is no threat to the International Space Station (ISS) and its crew as a result of the unsuccessful docking. The ISS, NASA added, was never in danger during the aborted docking attempt. On Saturday, Russia's space agency Roskosmos showed a live feed of what was expected to be the final stage of the journey.
The Soyuz is on safe trajectory above and behind the space station, NASA said.
NASA said in a later statement that the station's two Russian cosmonauts, overseeing the docking, issued a command to abort the docking at 1:36 a.m.
Fedor blasted off Thursday in a Soyuz MS-14 spacecraft from Russia's Baikonur cosmodrome in Kazakhstan and was to stay on the ISS until September 7.
"Let's go. Let's go", the robotic was heard saying throughout launch, repeating the well-known phrase utilized by first man in house Yuri Gagarin.
It stands around one meter and 80 centimeters tall and weighs 160 kilograms.
Although, As of now, this was the first attempt made by Russian Federation and Skybot F-850 is the first humanoid robot to have made it to the ISS.
Fedor has Instagram and Twitter accounts with posts saying it's studying new abilities resembling opening a bottle of water.
The life-size robot named FEDOR, short for Final Experimental Demonstration Object Research, is the first-ever sent up by Russian Federation.
The size of the Russian humanoid robot is the size of a normal human adult and it can complete tasks as a normal human body can.
The United States sent a robot into space in 2011 with the aim of working in high-risk environments.