England sit top of their Euro 2020 qualification group after three wins from three but it is surprise package Kosovo who are running them close in second place as the two nations prepare for their first-ever meeting.
There are now no Newcastle players in the England squad, despite the club having a strong core of English talent amongst their ranks.
But it is not the goals-for column that Southgate will be dwelling on, as he tries to make sure England are prepared for next summer's finals, which they are already all-but guaranteed to qualify for.
"I remember going to Spain and thinking "well, a really tough game, but actually you look at our front three and their front three on the night and I felt that we were strong".
"For me as a coach it is not easy to have a good mix for the evaluation of this game".
Bernard Challandes wishes Raheem Sterling was Kosovan
"I think Ole (Gunnar Solskjaer) has a young, energetic team, and I think Jesse's pressing and the energy he brings to that has been an important part of what they've tried to do in the first few games".
"They have the longest unbeaten record in Europe".
"I don't think you can have a player that is undroppable, because I think that's a risky route for any team and it's probably not healthy for any individual player", he added.
"Although we have, for a long time, nearly wanted Marcus to be that option as a [No] 9, I'm still not certain that that is where he is happiest and where he does his best work", Southgate said.
"We're in a healthy position", said Southgate before Tuesday's Euro 2020 qualifier against Kosovo at St Mary's. It's hard because there are so many new countries now and so many countries to involve in the process, but we've got to do the right thing for the supporters as well.
It's possibly Kosovo's biggest match and if they can't handle it there's every chance of a red in the match at 5-1 with Sky Bet. With John Stones expected to be fit for England's next fixtures Keane will likely drop out of the team, partly due to his latest mistake.