There have been six deaths across 33 states and 450 reported cases of lung illness tied to vaping.
The Trump administration is trying to ban all non-tobacco flavored vaping products from the market, President Trump declared during an Oval Office meeting on e-cigarettes. He said the ban will include mint and methanol flavors.
"The Trump administration is making it clear that we intend to clear the market of flavored e-cigarettes to reverse the deeply concerning epidemic of youth e-cigarette use that is impacting children, families, schools and communities", Azar said in a statement.
The Trump administration is moving to ban flavored e-cigarettes amid an outbreak of vaping-related lung disease.
The first lady, whose "Be Best" platform focuses in part on children's health and combating addiction, has spoken out a couple of times over her concerns over e-cigarette use by children.
He also said the agency would take enforcement action if they determined children are being intentionally attracted to e-cigarettes.
The decision comes amid outcry over the increase in teen vaping. "We need to do all we can to protect the public from tobacco-related disease and death, and prevent e-cigarettes from becoming an on-ramp to nicotine addiction for a generation of youth".
E-cigarette vapor contains tiny particles that carry flavorings.
According to reports compiled by Prescient & Strategic Intelligence, it's a billion-dollar industry that has some youth admitting to spending close to $1,000 a year to indulge.
NY state health authorities have focused their investigation on vitamin E acetate, which is used as a thickener in black market vaping cartridges.
Earlier this month, nearby MI became the first state in the nation to announce a ban on flavored e-cigarettes.
E-cigarettes have been on the USA market for more than a decade.
Azar said it will be several weeks before his department releases its proposal to crack down on flavored e-cigarettes.