All three face a giant obstacle after several states, including SC, made a decision to ditch their own 2020 GOP presidential primaries. "I think that as the Republican Party, we have lost our way", the presidential hopeful said in an interview with United States broadcaster Fox News.
KEITH: So in short, he thinks that President Trump needs a serious primary challenge, so there can be a conversation and debate about what it means to be a Republican, which he says hasn't really happened during the Trump presidency because President Trump is the leader of the Republican Party, and he tends to crush his opponents, like Sanford.
The Nevada Republican Party was expected to hold a vote on possibly changing its rules to allow a bypass of its presidential nominating caucuses in 2020 and endorse Pres. Trump outright.
"I am compelled to enter the Presidential Primary as a Republican for several reasons - the most important of which is to further and foster a national debate on our nation's debt, deficits and spending", Sanford said in a tweet announcing his candidacy.
Trump then flew to Fayetteville where he held a rally for Republican Dan Bishop in a closely-watched special election that is taking place today.
They said: "We will be giving President Trump the same treatment we have given every elected Republican dating back to Abraham Lincoln".
"This is nothing new, despite the media's inauthentic attempt to portray it as such", said Kelli Ward, chairman of the Republican Party of Arizona. "If you're shutting down primaries, you're a little nervous about how the dynamic of these primary challenges could go". Not here. Denying Americans the right to vote in order to protect Donald Trump?
When pressed on what he meant by "a dynasty", Parscale said, "I think they are all wonderful people with [.] unbelievable capabilities". Last spring, some 43% of Republicans told the Pew Research Center that they are open to a primary challenger to Trump. He enjoys wide popularity within his own party, but a GOP defeat in a red-leaning state could portend trouble for his reelection campaign.
"It's not as if I'm saying, you know, I think I can become president", he said.
As Sanford jumps into the race as the most competitive GOP challenger Trump has yet to face this cycle, the Republican Party, consistent with parties with an incumbent president in the White House running for re-election, has expressed firm support for Trump.
John Binder is a reporter for Breitbart News.
I mean, both men - Bill Weld is the former MA governor - Joe Walsh, former member of Congress.
Mr Sanford criticised Mr Trump during the 2016 presidential election but ultimately supported him.
Sanford's possible presidential motivations immediately drew skepticism from a primary opponent and some SC political observers who have watched him plot a political comeback before and questioned whether he was merely seeking publicity and relevance following a defeat in last year's primary.
MARK SANFORD: I think that the Republican Party has lost its way on what were traditional benchmarks to what the party has been about.